Topoisomerase II enzyme-DNA complex

Topoisomerase II–DNA Complex

This model shows the interaction between Topoisomerase II and a DNA double strand. Topoisomerase II controls DNA topology by creating temporary double-strand breaks (these are perfectly visible in this model) and resealing them. The complex model illustrates an essential mechanism for maintaining genome stability and visualizes the interaction between Topoisomerase II and DNA, making the molecular structure and mechanism easier to understand in a touchable way. 

Coloring: 

• Protein: red

• DNA: white

Print information:

• Printer: Prusa MK4S

• Supports required: Yes !!! Organic!!!

• Layer height: min. 0.2 mm recommended for nice surface quality

• Print scale: mind. 150% recommended; mine is 170%

• Filament type: PLA

• Infill percentage: 5% for protein; 10% for DNA

• Perimeters: 2 for protein; 3 for DNA

• USE organic supports !!! --> won't work otherwise

• print all parts separately like I did in the print files and assemble them afterwards with superglue